Showing posts with label DasGupta. Show all posts
Showing posts with label DasGupta. Show all posts

Sunday, March 30, 2014

Luciferase-based assays in cultured cells

Yun C, Dasgupta R. Luciferase reporter assay in Drosophila and Mammalian tissue culture cells. Curr Protoc Chem Biol. 2014 Mar 14;6(1):7-23. PMID: 24652620.

Tuesday, July 5, 2011

Breaking Report: Chemical Screen in RNAi knockdown background

On my desk to read this morning? A chemical screen in a background sensitized by RNAi. Screened in fly cells with follow-up in a mammalian system.

Gonsalves et al. 2011. An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway. Proc Natl Acad Sci U S A. 108(15):5954-63. PMID: 21393571; PubMed Central PMCID: PMC3076864.