Online Protocols Updated at DRSC

Please Note: We've recently updated our dsRNA protocols on-line. View them here.

Take Your Brain to Spain

Recently saw an announcement for this ESF-EMBO symposium: "Functional Neurobiology in Minibrains: From Flies to Robots and Back Again." 17-22 October 2010 in Sant Feliu de Guixols, Spain. Details here.

Quote of the Week

Everything is collage, even genetics.

- from Michael Ondaatje's Divisadero

Bloomington Resources Paper

What's on my desk to read today? A new paper from the Bloomington Drosophila Stock Center (BDSC) that includes information about resources from the TRiP (in vivo RNAi) that are available at the BDSC:

Cook et al. (2010) New research resources at the Bloomington Drosophila Stock Center. Fly. 4(1):1-4.

Breaking Report: Dissecting Signaling with RNAi

What's on my desk today? A newly published report based on extensive double knockdown RNAi screening that made use of DRSC resources.

Nir et al. (2010) Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen. in Genome Research.

Breaking Report: in vivo rescue

What's on my desk this morning? Another report on RNAi rescue in Drosophila:

Langer et al. (2010) In Vivo RNAi Rescue in Drosophila melanogaster with Genomic Transgenes from Drosophila pseudoobscura. PLoS One. 5(1):e8928. PubMed PMID: 20126626.

Related posts:

Tissue-Specific RNAi Rescue in Drosophila

Cross-Species RNAi Rescue in Cultured Drosophila Cells

Quote of the Week

Enjoying insects is much the same whether you do it in your own garden or in a distant country. The rule is to watch, and interfere as little as possible.

- H. Oldroyd in The Insects in Your Garden (1976, Penguin Books Ltd; England)

Meeting Announcement: Arthropod Genomics

Just received an announcement about the 4th Annual Arthropod Genomics Symposium, Arthropod Genomics: New Approaches and Outcomes. June 10-13 in Kansas City, MO.

Breaking Report: Fly RNAi & Huntington Disease Model

What's on my desk today?

A report that includes data from a genome-wide screen performed at the DRSC:

Zhang et al. (2010) A Genome-wide RNAi Screen for Modifiers of Aggregates Formation by Mutant Huntingtin in Drosophila. Genetics. 2010 Jan 25. [Epub ahead of print] PubMed PMID: 20100940.

The paper includes a note added during preparation comparing these results with results of a similar study by Doumanis et al. (2009) [blogged about here last fall ], as well as comparison with similar work in C. elegans.