Wednesday, September 26, 2012

Then & Now: Jak/Stat screening. Breaking report.

Fisher KH, Wright VM, Taylor A, Zeidler MP, Brown S. Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway. BMC Genomics. 2012 Sep 24;13(1):506. PubMed PMID: 23006893.

Tuesday, September 25, 2012

Thursday, September 13, 2012

DIOPT-DIST updated for 'fuzzy' search

The "disease full text search" field at the DRSC's only tool DIOPT-DIST, which is useful for matching up fly (or other model system) genes to human genes associated with diseases or traits, is now more forgiving of misspellings. Trying different synonyms for a given disease is still a good idea. Another tip:  On the search results page, click the DIOPT score to get a protein alignment.

Wednesday, September 12, 2012

Breaking Report: Cell-basd RNAi protocol

Ravi D, Bishop AJ. Identification of Genes Required for Damage Survival Using a Cell-Based RNAi Screen Against the Drosophila Genome. Methods Mol Biol. 2012;920:9-26. PubMed PMID: 22941593.

Friday, September 7, 2012

Appeal for support letters -- FlyAtlas

The authors of FlyAtlas are appealing for email letters of support as they apply for a new round of funding. If you're a FlyAtlas user, please consider voicing your support. At the DRSC and TRiP, we have seen the resource useful to researchers at both planning and analysis stages. As of this posting, the appeal for email letters of support is on their home page.