Showing posts with label phosphatases. Show all posts
Showing posts with label phosphatases. Show all posts

Monday, September 5, 2011

Breaking Report: Huntington's Disease Model Study

On my desk today? A very recent report from Schulte, Sepp et al. using Drosophila primary cells. The study included screening of the DRSC Kinases & Phosphatases library.

Schulte, et al. (2011) High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington's Disease Model. Open access at PLoS One 6(8): e23841

Thursday, May 26, 2011

Kinases & Phophatases

The list associated with the DRSC Kinases & Phosphatases library has been updated.

The downloadable spreadsheet now indicates which genes encode known or predicted kinases, and which encode known or predicted phosphatases. The new list also shows the updated FlyBase IDs (FBgn Numbers) and gene symbols, along with the IDs and symbols that appeared on the older version of the list. The library has close to 3 unique reagents per gene.

On the assay plates themselves, the two categories are mixed up together so it's not possible to screen just kinases or just phosphatases (we get asked that fairly often).