Monday, April 15, 2013

Acentriolar cell lines. Recent report.

Lecland N, Debec A, Delmas A, Moutinho-Pereira S, Malmanche N, Bouissou A, Dupré C, Jourdan A, Raynaud-Messina B, Maiato H, Guichet A. Establishment and mitotic characterization of new Drosophila acentriolar cell lines from DSas-4 mutant. Biol Open. 2013 Mar 15;2(3):314-23. doi: 10.1242/bio.20133327. PubMed PMID: 23519377; PubMed Central PMCID: PMC3603413.

From the abstract: "pilot RNAi experiments open the potential use of these cell lines for the molecular dissection of anastral pathways in spindle and centrosome assembly."

Wednesday, April 3, 2013

Flies & phosphate. Breaking report.

This paper includes report of a full-genome cell-based RNAi screen performed at the DRSC and in vivo RNAi follow-up.

Bergwitz C, Wee MJ, Sinha S, Huang J, Derobertis C, Mensah LB, Cohen J, Friedman A, Kulkarni M, Hu Y, Vinayagam A, Schnall-Levin M, Berger B, Perkins LA, Mohr SE, Perrimon N. Genetic determinants of phosphate response in Drosophila. PLoS One. 2013;8(3):e56753. PubMed PMID: 23520455; PubMed Central PMCID: PMC3592877.