Travel Grants for Interdisciplinary Collaborations

Just saw this announced: Burrows Welcome Fund Collaborative Research Travel Grant.

From their website: "This program provides ... support for researchers ... to travel ... to a laboratory to acquire a new research technique, to facilitate/begin collaboration, or to attend a course. Applicants must hold a Ph.D. or are studying for a Ph.D. in mathematics, physics, chemistry, computer science, statistics, or engineering who are interested in investigating research opportunities in the biological sciences or to biologists interested in working with physical scientists, mathematicians, engineers, chemists, statisticians, or computer scientists to incorporate their ideas and approaches to answering biological questions."

SILAC & RNAi

Also on my desk today? A chapter with protocols on combining SILAC-labeling and mass spec with RNAi in Drosophila cultured cells.

Cuomo and Bonaldi (2010) Systems Biology “On-the-Fly”: SILAC-Based Quantitative Proteomics and RNAi Approach in Drosophila melanogaster. Methods Mol Biol. 662:59-78.

Breaking Report: Jak/Stat

What's on my desk to read today? A report that includes screening of a focused set of 67 candidate genes in Kc cells.

Vidal et al. (2010) Negative regulation of Drosophila JAK-STAT signalling by endocytic trafficking. J Cell Sci. 2010 Sep 14. [Epub ahead of print]

New on the DRSC Website

We've just added a map showing empty and control wells on an example plate from the Kinases & Phosphatases set on the sub-libraries web page. For 'the subs' we leave empty wells around the edges to minimize the potential impact of edge-effects on experimental data.

Meeting Announcement

Just received an announcement for the 5th Annual Arthropod Genomics Symposium, June 9 to 12, 2011, Kansas City Marriott on the beautiful Country Club Plaza.

Methods Video

What am I watching today? A new video on fly RNAi methods.

Moser et al. (2010) RNAi Screening for Host Factors Involved in Vaccinia Virus Infection using Drosophila Cells. J Vis Exp. 2010 Aug 25;(42). pii: 2137. doi: 10.3791/2137.

Just the Facts, Please

We've just updated our Assay Overview page, which describes the instruments available at the DRSC (or at collaborating facilities) for high-content imaging, plate-reader, etc. screens. It's not beautiful design but we hope it gives the information folks need.

Breaking Report: Wound Closure

What's on my desk today? A screen of ~200 in vivo RNAi lines from the VDRC & NIG-Fly collections to identify genes involved in wound closure.

Lesch et al. (2010) A Targeted UAS-RNAi Screen in Drosophila Larvae Identifies Wound Closure Genes Regulating Distinct Cellular Processes. in Genetics.

Presentation on in-cell in situ at HMS

Are you local? The ICCB-Longwood Screening Facility is hosting a workshop on in situ in cells (the Quantigene ViewRNA technology from Affymetrix). See the ICCB-L website for details.