Breaking Report: Cell Profiler 2.0

On my desk to read today? A report on an updated version of the open source Cell Profiler software for screen image data analysis.

Kamentsky et al. (2011) Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software. Bioinformatics. 27(8):1179-80.

Breaking Report: RNA Splicing

I haven't quite got my hands on a copy of the article yet but I am looking forward to reading this:

Ashton-Beaucage and Therrien (2011) The exon junction complex: A splicing factor for long intron containing transcripts? Fly. Jul 1;5(3). PMID: 21478676

Even more catching up to do

Later the same day, and I'm still catching up on past posts. Here is another I might have missed--UPDATE: No, I didn't. It was posted. But I'll leave this up anyway.

Saj et al. (2010) A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network. Dev Cell. 2010 May 18;18(5):862-76.

In the future I might start tagging by topic and/or authors. Make it easier for myself and others to figure out what was posted before.

Breaking Report (Catching up!): 14-3-3zeta in phagocytosis and resistance, and, AP-3 in sorting

On my desk today? Catching up on two papers I think I missed.

Ulvila et al. (2011) Cofilin regulator 14-3-3{zeta} is an evolutionarily conserved protein required for phagocytosis and microbial resistance. J Leukoc Biol. PMID: 21208897

Asensio et al. (2010) RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway. J Cell Biol. 2010 Dec 13;191(6):1173-87.

If you see something appropriate to the blog that I seem to have missed, please feel free to let me know by commenting on the blog or by email!

Web Wednesday: Antibodies against Drosophila Antigens

Just got notification of new additions in the set of antibodies against Drosophila antigens present in the collection at the Developmental Studies Hybridoma Bank. Take a look.

Breaking Report from the Transgenic RNAi Project (TRiP)

On my desk today? A breaking report from our lab space colleagues with the Transgenic RNAi Project (TRiP) here at Harvard Med School.

Ni et al. (2011) A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nature Methods (e-published today ahead of print). PMID: 21460824.