Thursday, September 5, 2013
Fly RNAi & Huntingtons disease.
The paper displayed at this post at Drosophila Models of Human Diseases fits here as well--Lu and colleagues describe the results of genome-wide RNAi screens in fly cells plus in vivo fly follow-up in a disease model mutant.
Another fly CRISPR report.
Early online at Genetics--this report from Kondo and Ueda on using CRISPRs in flies.
Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila. Genetics. Early online September 3, 2013, doi:10.1534/genetics.113.156737.
Highly Improved Gene Targeting by Germline-Specific Cas9 Expression in Drosophila. Genetics. Early online September 3, 2013, doi:10.1534/genetics.113.156737.
RNAi validation with a synthetic transcript
On my desk to read this week?
Jonchere V, Bennett D. Validating RNAi Phenotypes in Drosophila Using a Synthetic RNAi-Resistant Transgene. PLoS One. 2013;8(8):e70489. PMID: 23950943; PMCID: PMC3738578.
Jonchere V, Bennett D. Validating RNAi Phenotypes in Drosophila Using a Synthetic RNAi-Resistant Transgene. PLoS One. 2013;8(8):e70489. PMID: 23950943; PMCID: PMC3738578.
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