On my desk today? A report that uses RNAi to study an aspect of RNA biology--in this case, knockdown of specific exosome factors followed by genome-wide analysis of mRNAs is used to gain insight into exosome functions.
Kiss & Andrulis (2010) Genome-wide analysis reveals distinct substrate specificities of Rrp6, Dis3, and core exosome subunits. RNA 16: 781-791. doi: 10.1261/rna.1906710
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