Monday, May 3, 2010

Breaking News: NF-kappa-B Genome-wide Drosophila cell RNAi screen

What's on my desk to read today? A report of a genome-wide fly RNAi screen designed to query the NF kappa B pathway. Includes follow-up studies in zebrafish using morpholinos to knock down gene function in that organism.

Valanne et al. (2010) Genome-Wide RNA Interference in Drosophila Cells Identifies G Protein-Coupled Receptor Kinase 2 as a Conserved Regulator of NF-{kappa}B Signaling. J Immunol. 2010 Apr 26. [Epub ahead of print]. PMID: 20421637.

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