Thursday, October 14, 2010

Recent Review: miRNAs & Cancer

What's on my desk to read today? A recent review on miRNAs and cancer.

This review is not directly relevant to using RNAi for screens, of course. But Fig. 4 is a nice summary of tools for disrupting miRNAs. And I like to try to keep up with aspects of RNA biology, as understanding RNA biology is interlinked with exploiting it as a research tool.

Garzon et al. (2010) Targeting microRNAs in cancer: rationale, strategies and challenges. Nature Reviews Drug Discovery 9: 775-789. Available FREE.

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