Breaking Report: Pathogen Screen

On my desk to read today? A pathogen screen in S2 cells.

Qin et al. (2011) Functional Analysis of Host Factors that Mediate the Intracellular Lifestyle of Cryptococcus neoformans. PLoS Pathog. 7(6):e1002078. PMID: 21698225.

Similar interest in screening a relatively small set of genes? The DRSC will cherry-pick from our collection of high-quality amplicons and make dsRNA for your custom screen.

Going for the Kill

On my desk to read today? A paper that describes using in vivo RNAi to sensitize strains, then test potential insecticides for activity that might otherwise be masked by a wild-type organism's ability to detox.

Shah et al. (2011) Insecticide detoxification indicator strains as tools for enhancing chemical discovery screens. Pest Manag Sci. doi: 10.1002/ps.2218. PMID: 21681918.