On my desk to read today? A report on a full-genome screen performed at the DRSC.
The authors include information that might be generally useful to screeners, particularly those performing or currently analyzing the results of luciferase-based assay readouts. The study also includes follow-up using in vivo RNAi.
Aikin et al. (2012) A Genome-Wide RNAi Screen Identifies Regulators of Cholesterol-Modified Hedgehog Secretion in Drosophila. PLoS One. 2012;7(3):e33665. PubMed ID: 22432040