Thursday, February 20, 2014

in vivo screen looks at role of RNA binding proteins in neuron morphogenesis

Olesnicky EC, Killian DJ, Garcia E, Morton MC, Rathjen AR, Sola IE, Gavis ER. Extensive Use of RNA Binding Proteins in Drosophila Sensory Neuron Dendrite Morphogenesis. G3 (Bethesda). 2013 Dec 20. pii: g3.113.009795v2. PMID: 24347626.

From the abstract:  "... we conducted an RNAi screen to identify Drosophila proteins annotated as either RNA binding proteins or translation factors that function in producing the complex dendritic trees of larval class IV dendritic arborization neurons. We identified 88 such proteins whose knock-down resulted in aberrant dendritic morphology ..."

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