Saturday, September 27, 2014
Study related to Abl kinase uses primary cultured cells
This is not an RNAi study but the approach taken might of interest to those thinking about cell-based studies. Liu L, Wu CF. Distinct effects of Abelson kinase mutations on myocytes and neurons in dissociated Drosophila embryonic cultures: mimicking of high temperature. PLoS One. 2014 Jan 21;9(1):e86438. PMID: 24466097; PMCID: PMC3897706. From the abstract: "... we observed myocyte fusion events and nerve-muscle contact formation between WT and Abl cells in mixed WT and Abl cultures derived from labeled embryos ..."