What's on my desk today? A pair of research reports and an accompanying opinion piece published last fall (November 2008) from R. Moon's lab. The opinion piece emphasizes the power of integrating results obtained via multiple high-throughput strategies. The research reports present examples of these types of integrated studies, with a focus on Wnt/beta-Catenin signaling.Major et al. (2008) New regulators of Wnt/beta-Catenin signaling revealed by integrative molecular screening. Science Signaling 1:ra12.
James et al. (2008) Bruton's Tyrosine Kinase revealed as a negative regulator of Wnt-beta-Catenin signaling. Science Signaling 2:ra25.
Major & Moon (2008) "Omic" risk assessment. Science Signaling 2:eg7.
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