At the DRSC we recently tested a new commercial plate type supporting growth of cells in very small volumes of media--tiny domes of liquid in 96- or 384-well format. We have not had time for much testing but we can say this: S2R+ cultured Drosophila cells grew just fine in this format in our hands. Photo below. Feel free to email the DRSC Director if you have any questions. DropArray plates from Curiox. Posting this for information purposes only (should not be considered an endorsement).