Thursday, January 29, 2015

CRISPR-based gene photoactivation system

Nihongaki Y, Yamamoto S, Kawano F, Suzuki H, Sato M. CRISPR-Cas9-based Photoactivatable Transcription System. Chem Biol. 2015 Jan 20. pii: S1074-5521(14)00459-1. PMID: 25619936.

From the abstract: "... Here we created a light-inducible, user-defined, endogenous gene activation system based on CRISPR-Cas9. ... this ... system can allow rapid and reversible targeted gene activation by light."

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